Technical Operations Manager

The role is located in Leiden, Zuid-Holland, in the Pharmaceuticals sector, with a start date of 9/23/2026 and job reference 59052. Our client is a global healthcare organization with a newly established lentiviral vector manufacturing facility in Sassenheim. The facility supports commercial production within a highly regulated GMP environment, with a strong focus on technical excellence, quality and continuous improvement. As Technical Operations Manager, you will lead a team of around 15 technical specialists supporting manufacturing operations.

You will oversee technical improvements, equipment and single-use solutions, complex problem solving and cross-functional projects, while ensuring GMP, safety and quality requirements are met. Key responsibilities include leading and developing the CoE team of technical specialists; overseeing technical changes and equipment and single-use improvement projects; providing technical expertise and supporting the resolution of complex process issues; partnering with Operations, QA, QC, MSAT, IT and other functions on technical projects; driving improvements focused on quality, cost, cycle time and capacity; supporting new product and process implementation within manufacturing; reviewing and approving technical documentation and specifications; monitoring equipment performance, maintenance and recurring technical issues; allocating resources to deliver projects within agreed timelines and budgets; and promoting innovation, Lean and continuous improvement within the facility.

Requirements include 10+ years of experience in a pharmaceutical GMP production environment; 6+ years of people leadership experience at Supervisor or Manager level; strong knowledge of GMP and pharmaceutical manufacturing processes; proven experience delivering Lean projects, both technically and as a leader; experience with technical projects involving equipment, materials or single-use systems; knowledge of EHSS and regulatory requirements in a GMP environment; strong leadership, decision-making and stakeholder management skills; ability to work effectively in a complex, cross-functional environment; and knowledge of JJOS methodology and systems is an advantage.